Systems, methods and computer accessible medium are provided through which an input data stream consisting one or more media regions before entering a network to be rendered by a display coupled a remote video frame buffer is compressed on the basis of one or more configuration file metadata, source primitive metadata, and application high-level metadata of identified media regions. The input data stream is compressed by using one or more MPEG compression, JPEG compression, vector graphics compression, Huffman coding, or user defined compression scheme.