A multi-player audio game system and game console enables players to compete against each other based on music that is contained in their own personal music player devices. The game console has multiple ports to allow the players to plug their audio player devices into the game console. In response to pressing a Next button to advance the game, the console displays a music question or challenge selected from questions stored in memory. Upon seeing the challenge displayed, the players compete to be the first to submit a music entry (by playing their entry and pressing the respective Enter button on the console) that meets the challenge from among the songs stored on their audio player devices. The console has an audio signal queuing mechanism to allow the first-in-time player's song input to be played on a speaker while muting the other players' song inputs. If the first-in-time player's entry is deemed incorrect by the other players, the player's Enter button can be pressed a second time to mute that player's song input and allow the next-in-time player's song input to be played, and so on until a winner is found.