A wide latitude printing system is provided for printing on a wide variety of different types, sizes, formats and weights of media substrates. The wide latitude printing system includes (a) at least one floor standing and movable marking engine assembly having an imaging member, devices for forming an image on the imaging member, (b) a floor standing and separately framed dockable and undockable transfix module for side by side docking with the marking engine assembly, the dockable and undockable intermediate transfix module including an intermediate transfer member for receiving the image from the marking engine assembly, and (c) a floor standing dockable and undockable media supply and handling module for side by side docking with the dockable and undockable transfix module, the dockable and undockable media supply and handling module including a set of different types of media substrates for receiving the image from the intermediate transfer member onto one of the set of different types of media substrates.