The high-pressure mixing apparatus, for reactive chemical components, comprises a device for self-lubricating and scraping the outlet duct of the chemical mixture, and flushing out the scraped residues. The self-lubricating and scraping device comprises a delivery chamber for the lubricant material axially aligned and in fluid communication with the outlet duct; the lubricant delivery chamber is connected to a storage tank by a feeding and re-circulation circuit. The lubricant is sucked into the outlet duct and subsequently returned into the delivery chamber by a cleaning member in the form of a pumping piston sliding into the outlet duct, the pumping piston being provided with scraping rings for removing the reacted mixture adhered to the inner surface of the outlet duct.