A system for personal medical care, intelligent analysis and diagnosis may include: at least one source of medical information; at least one source of personal medical data for at least one patient; and one or more servers, where the medical information and the personal medical data are accessible to the server(s). The server(s) may include: an artificial intelligence (AI) component for analyzing the personal medical data with the medical information and identifying at least one issue requiring follow-up by the patient or by at least one external authorized entity; and at least one real-time communication link for bi-directional communication with at least one external authorized entity.