A composition and method of applying to skin which has psoriasis a gel that contains curcumin and/or curcuminoids. Prior to applying of the gel to the skin, the affected layer is soaked in one-hundred percent alcohol. The alcohol functions to dissolve the curcumin and/or curcuminoids with the alcohol not only comprising a solvent but functions as a carrier to cause the freshly dissolved (nascent) curcumin to penetrate through the stratum corneum layer of the skin and into the epithelial layer of the skin.