Provided is a method of treating a patient suffering from a pain state by
administering to the patient a gastric retentive dosage form of
gabapentin that is capable of administration in once-daily or twice daily
dosing regimens. By reducing the need to administer gabapentin from the
thrice-daily administrations characteristic of immediate release
gabapentin, the gastric retentive gabapentin dosage forms provided herein
have the advantages of improving patient compliance for gabapentin
treatment. In addition to the foregoing, the gastric retentive gabapentin
dosages forms also exhibit decreased blood plasma concentrations and
increased bioavailability throughout the dosing regimen.