A sensor for the detection or measurement of a carbohydrate analyte in
fluid comprises components of a competitive binding assay the readout of
which is a detectable or measurable optical signal retained by a material
that permits diffusion of the analyte but not the assay components, the
assay components comprising: a carbohydrate binding molecule labelled
with one of a proximity based signal generating/modulating moiety pair;
and a carbohydrate analogue capable of competing with the analyte for
binding to the carbohydrate binding molecule, the carbohydrate analogue
being a flexible water-soluble polymer comprising: polymerized or
co-polymerised residues of monomer units, the monomer unit residues
bearing pendant carbohydrate or carbohydrate mimetic moieties and pendant
moieties which are the other of the proximity based signal
generating/modulating moiety pair.