Methods for forming an integral porous region in an orthopedic implant are provided. The method uses an orthopedic implant pattern, together with a porous framework having a plurality of reticulated interstices in a molding technique. After filling the mold with a molten metal such that the molten metal enters at least a portion of the reticulated interstices, followed by cooling, an orthopedic implant is formed. The porous framework is then removed to expose an integral porous region of reticulated porosity in the implant. The orthopedic implant may comprise a monolithic metallic body having an integral porous metal region. Reticulated porosity extends into the monolithic metallic body and is adapted to allow living tissue growth therein.