A method of controlling both alignment and registration (lateral position)
of lamellae formed from self-assembly of block copolymers, the method
comprising the steps of obtaining a substrate having an energetically
neutral surface layer comprising a first topographic "phase pinning"
pattern and a second topographic "guiding" pattern; obtaining a
self-assembling di-block copolymer; coating the self-assembling di-block
copolymer on the energetically neutral surface to obtain a coated
substrate; and annealing the coated substrate to obtain micro-domains of
the di-block copolymer.