Compounds of formula Ia or Ib: ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined herein. Also disclosed are methods of making the compounds and methods of using the compounds for treatment of p38 MAP kinase-mediated diseases.

 
Web www.patentalert.com

< Substituted pyrazolo[3,4-D]pyrimidines as p38 map kinase inhibitors

> Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases

> Piperazine-piperidine antagonists and agonists of the 5-HT.sub.1A receptor

~ 00534