The present invention provides methods for cleaning surfaces that are sensitive to high temperatures and/or that have pH limitations. Exemplary surfaces to be cleaned using the methods of the present invention include membranes. The methods of the present invention include applying an active oxygen use solution including an active oxygen source to the surface. An activator complex and an alkaline override use solution are applied to the surface, either in combination, or in a stepwise manner, before, after or simultaneously with the active oxygen use solution.