Certain embodiments of the present invention provide a system and method for identifying stool particles in virtual dissection data for a colon. A shape classification may be determined for a segmented colon by three-dimensional filtering of a prone data set and a supine data set. The shape classification may be mapped onto a prone virtual dissection image and a supine virtual dissection image. The prone data set and the supine data set may be registered using one-dimensional registration to determine a registration. Shapes may be localized based on the shape classification and the registration for the prone virtual dissection and the supine virtual dissection. A distance metric may be applied to the localized shapes to identify stool particles. The identified stool particles may be suppressed. A prone virtual dissected image and a supine virtual dissected image may be displayed having the stool particles suppressed.