A grille arrangement for an enclosure of a drive unit of a self-propelled agricultural applicator is provided. The grille arrangement includes a screen, and a frame mounted by the screen. The frame includes a first strut connected by at least one movable latch assembly to the enclosure, and a second strut having a first linear portion aligned at an obtuse angle relative to a second linear portion in top plan view. The screen is attached at the first linear portion. With the frame and screen aligned at the obtuse angle relative to a vertical plane perpendicular to a forward direction of travel, the second linear portion slides into a notch at a vertical support strut fixed at the enclosure. Upon sliding the second linear portion in the notch, rotation of the frame rotates the second linear portion to a lock position securing the frame and screen at the enclosure.