An apparatus for localizing a focal lesion in a biological tissue section applies electrical excitation signals to the tissue section and measures electrical response signals at a number of measurement locations on a surface of the tissue section that arise there due to the excitation signals. A computer reconstructs a distribution of electrical dipole moments from the response signals, this distribution of dipole moments overall best reproducing the response signals, and supplies the 3D spatial position of the distribution as an output.

 
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