The present invention relates to certain novel compounds of the formula
(I) to processes for preparing such compounds, to their the utility in
modulation of nuclear hormone receptors Liver X Receptor (LXR) .alpha.
(NR1H3) and/or .beta. (NR1H2) and in treating and/or preventing clinical
conditions including cardiovascular diseases such as atherosclerosis;
inflammatory diseases, Alzheimer's disease, lipid disorders
(dyslipidemias) whether or not associated with insulin resistance, type 2
diabetes and other manifestations of the metabolic syndrome, to methods
for their therapeutic use and to pharmaceutical compositions containing
them. ##STR00001##