A method for treating gastric acid disorders with a non-enteric coated
proton pump inhibitor in a pharmaceutically acceptable carrier including
a bicarbonate salt of a Group IA metal and a carbonate salt of a Group IA
metal; and a pharmaceutical composition of a non-enteric coated proton
pump inhibitor in a pharmaceutically acceptable carrier including a
bicarbonate salt of a Group IA metal and a carbonate salt of a Group IA
metal are disclosed. A presently preferred proton pump inhibitor is
lansoprazole, a presently preferred bicarbonate salt is sodium
bicarbonate, and a presently preferred carbonate salt is sodium
carbonate. The composition is a fast-acting formulation which reduces the
undesirable belching associated with proton pump inhibitor formulations
that contain high doses of sodium bicarbonate.