The present invention relates to a carboxylic acid compound of formula (I): ##STR00001## wherein R.sup.1 is H, alkyl; m is 2, 3; n is 0-2; R.sup.2 is phenyl, naphthyl, benzofuran, benzothiophene; Q is --CH.sub.2--O-Cyc1, --CH.sub.2-Cyc2, -L-Cyc3; R.sup.3a and R.sup.3b each independently is hydrogen, alkyl or taken together form tetrahydro-2H-pyran; a pharmaceutically acceptable salt thereof, a method for producing a process of the preparation thereof and a pharmaceutical agent comprising the same as an active ingredient. The compound of formula (I) have an antagonizing activity against PGE.sub.2 receptor, specifically EP.sub.3 receptor which is subtype thereof, and are useful for the prevention and/or treatment of itching, pain, urinary disturbance or stress disease.

 
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