A thermostat system having dedicated informational regions in a display and associated buttons or softkeys for sequential operation. The system may maximize utilization of a sectioned display and buttons for system navigation. The informational, selection and/or action design takes into consideration operational button groupings for straightforward comfort settings as well as editing of the clock, day-of-week, schedules, and so forth. Sections, regions or areas of the display may indicate immediate button operations. The changeable information in the regions associated with the softkeys or buttons may provide sequential operation of the thermostat system. The system may have multiple schedules and setpoints for heating and cooling comfort setting flexibility. A combining of individual schedules may be automatically selected. Also, there may be a system switch mode, for example, between heat and cool, where the schedules may be individually edited. Scheduling may be informational and/or action item and option key driven.