A pair of panties with a skin-whitening effect comprises a wearing space defined therein, and one or more gel blocks each covered by a release film attached to the panties so as to press close to a groin, a waist, and borders between hips and legs of a user to wear the panties. Thereby, after the release film is torn and the panties are worn by the user, skin-whitening, skin-color-lighting, and wrinkle-softening agents contained in the gel blocks can perform skin-whitening, skin-color-lighting, and wrinkle-softening treatment on the above-mentioned user's body portions, while not disturbing the user's daily life.