A gaming device in which primary game symbols are generated in association with secondary symbols. The secondary symbols if generated in a particular combination and in a particular situation, e.g., in association with winning base game symbols, provide a benefit to the player, such as a modification of a payout provided from the base or primary game win. In one embodiment, multiple secondary symbols appearing on slot machine reels are evaluated for a win. In another embodiment, a match between a secondary symbol appearing on slot machine reel and a secondary symbol appearing on a separate secondary reel yields a win. In a third embodiment, a winning combination of at least one secondary symbol appearing on slot machine reel in combination with a secondary symbol appearing on a separate secondary reel yields a win.