A process for applying a two-tone color effect coating to a substrate including applying an accent powder basecoating composition including film-forming material; reaction product as described herein; flow control agent; and first color effect additive, to a first predetermined portion of a surface of a substrate; at least partially curing the accent basecoating; applying a main liquid or powder basecoating composition having a different color effect additive to a second predetermined portion of the substrate, such that a portion of the accent basecoat is not contacted by the main basecoating composition; at least partially curing the main basecoating composition; applying a topcoating composition over the accent basecoat and main basecoat and curing the resulting composite coating, such that the first portion of the substrate has a different color effect than the second portion of the substrate to provide a two-tone color effect coated substrate.