Matrix material for a substantially immunologically-compatible meniscal
augmentation device of biocompatible and partially bioresorbable fibers
is prepared by treatment with oc-galactosidase to eliminate oc-Gal
epitopes. Upon implantation into a segmental defect of a meniscus, the
composite of the meniscal augmentation device and the meniscus
establishes a scaffold adapted for ingrowth of meniscal
fibrochondrocytes.