A system and method for controlling an application of a friction modifying agent to an area of contact between a railway wheel and a railway rail over which the wheel is traversing to selectively modify the coefficient of friction at the contact area. A sensor is used for detecting a parameter relating to the operation of the railway train. A controller is responsive to the sensor for selecting one or more of a plurality of friction modifying agents and controls the application of the agent to the rail as a function of the parameter. An applicator is responsive to the controller and applies the friction modifying agent to the area of contact between the railway wheel and rail. A second application of the agent may be predicated upon the effectiveness of a first application of the agent. The selection of the appropriate agent may include a consideration of a current location of the railway vehicle.