A single dose hygienic tooth whitener dispenser and applicator has a chamber. The housing is a bottle having an upper end with a neck and threads receiving a threaded sleeve. The sleeve includes a recess receiving a sponge applicator having a bottom surface overlying an upwardly facing opening of the chamber in the bottle. This opening is initially covered by a hermetic seal. An over-cap includes a bottom facing opening slidable over the sleeve and covers the applicator. Within the over-cap, a pin extends downwardly. The pin has a pointed end facing downward. When it is desired to use the inventive device to whiten the user's teeth, the over-cap is pushed down until the pointed end of the pin extends through the applicator and pierces the seal in the opening of the bottle, whereupon tooth whitener may be dispensed and applied.