A composition for use in an aerosol inhaler, the composition comprising an
active material, a propellant containing a hydrofluoroalkane (HFA), a
cosolvent and further comprising a low volatility component to increase
the mass median aerodynamic diameter (MMAD) of the aerosol particles on
actuation of the inhaler, filling of an aerosol container and use of the
composition for the administration of active materials by inhalation.