A colonic delivery solid preparation containing chitosan powder, which can
control the dissolution of a medicament therefrom in the large intestine
and release the medicament contained therein specifically in the large
intestine, obtained by successively coating a medicament-containing solid
material with (1) a water-insoluble polymer having a chitosan powder
dispersed therein and (2) an enteric polymer; and a solid preparation
containing chitosan powder, which can partly release a medicament in the
stomach and, after passing through the small intestine, disintegrate at
an accelerated rate in the large intestine and release a medicament in
the large intestine, obtained by coating a medicament-containing solid
material with a water-insoluble polymer having a chitosan powder
dispersed therein.