Novel non-steroidal compounds are provided which are useful in treating
diseases associated with modulation of the glucocorticoid receptor, AP-1,
and/or NF-.kappa.B activity including obesity, diabetes, inflammatory and
immune diseases, and have the structure of formula (I) ##STR00001## or
stereoisomers or prodrugs or solvates or pharmaceutically acceptable
salts thereof, wherein A, B, J, K, Z, R, R.sup.a, R.sup.b, R.sup.c, and
R.sup.d, are defined herein. Also provided are pharmaceutical
compositions and methods of treating obesity, diabetes and inflammatory
or immune associated diseases comprising said compounds.