The present invention concerns exploiting a characteristically negative behavior, such as habitual behavior or addiction, for example, for a beneficial purpose. In particular aspects, an individual desires eating healthy comestibles that comprises a positively-reinforcing compound, thereby consuming greater quantities of one or more healthy comestibles. In particular aspects, an obese or overweight individual loses weight and/or lowers BMI by consuming at least one healthy comestibles comprising the positively-reinforcing compound. In other aspects, an individual with a medical condition that could benefit from one or more particular comestibles consumes the one or more particular comestibles comprising a positively-reinforcing compound.