Information is compounded in medical diagnostic ultrasound. Volumes from multiple acoustic windows for the infant head are aligned and combined. The combination provides a dataset better representing the entire region of interest. Additionally or alternatively, weighted combination of ultrasound data sets is provided. The weights adapt as a function of proximity to the transducer (e.g., near field verses far field), noise level, or other data quality parameters. In the infant head example, the adaptive weights may provide a composite data set better representing the infant head. Adaptive weights for the compounding may be used in situations other than an infant head scan.