In one embodiment, a system comprises one or more input/output (I/O) devices; an I/O memory management unit (IOMMU) coupled to receive memory requests sourced by the I/O devices and configured to provide address translation for the memory requests; and a virtual machine monitor (VMM) configured to manage one or more virtual machines on the system, wherein the VMM is configured to virtualize the IOMMU, providing one or more virtual IOMMUs for use by one or more virtual machines.