According to the invention, a sampling system for spectroscopic measurements of a biological sample is disclosed. The sampling system includes a plurality of illumination points, a plurality of detection points, a memory, and a processor. Each of the plurality of illumination points is involved in at least two measurements of illumination through the biological sample. Each of the plurality of detection points is involved in at least two measurements of illumination through the biological sample. The memory stores a plurality of measurements. The processor determines a value from the plurality of measurements that is related to the biological sample.