System and method for periodic body scan differencing for detecting changes in surface and subsurface body scans over time. May include use of a scanner and a computer system configured to scan a portion of body at first point in time to yield first scan, scan the portion of the body at second point in time to yield second scan, difference the two scans to produce a morphological difference image, and display the morphological difference image. May utilize surface or subsurface scans. Any type of scanner may be utilized that scans to the desired resolution of morphological testing. Can morph scan(s), geometrically, visually or both, to account for age, weight or color differences that have occurred between scans. Can display morphological surface or subsurface differences between scans in multiple images or atlas view. Differences can be displayed independently or overlaid onto scan(s). Differences may be highlighted to make more readily viewable.