Mechanisms for splitting responsibilities for communicating with an endpoint between a device driver and device driver services are provided. With these mechanisms, the device driver is responsible for managing queues for communicating requests between applications in a logical partition and the endpoint. The device driver further invokes memory management via device driver services. The device driver services are responsible for managing memory accessible by the endpoint, including the address translation and protection table (ATPT) or a root complex and the address translation caches (ATCs) of the endpoint. The device driver services may associate untranslated addresses for data structures used to communicate between a system image and the endpoint. The endpoint may request translations of the untranslated addresses and may cache the translations in the ATCs.