The present invention relates to plant proteins produced by a plant's
epidermal layer that contribute to the innate pest/disease resistance of
the plant ("phylloplanins`), compositions comprising the phylloplanins
and methods of using the them. In particular the methods relate to
inhibiting or prevent microbial, e.g., fungal or bacterial, growth on a
subject, organism or surface, particularly inhibiting or preventing
spoilage of food products due to microbial infection and growth. The
invention also relates to transformed host cells that produce the
phylloplanins, and to transgenic plants producing phylloplanins
conferring increased resistance to microbial infections/growth.