A method, system, and computer program code for integrating components with different interfaces in an enterprise application integration environment. When an enterprise application is assembled, a user may try to wire a component to another component in the enterprise. However, if the reference on the source component does not match the interface on the target component, the components cannot be wired together. In this situation, the user is prompted to introduce an interface mediation component between the source and target application components. The mediation component comprises an interface matching the reference on the source component and a reference matching the interface on the target component. The mediation component mediates the different interfaces at runtime by binding an operation in the source component to an operation in the target component, and performing a parameter mediation of parameters in the first operation to parameters in the second operation.