Compounds of formula (I) possess unexpectedly high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders.In one embodiment, the invention features a compound of the general formula (I). ##STR00001##

 
Web www.patentalert.com

< Antibodies which bind specifically to activin receptor like kinases

> Method and apparatus for the treatment of the intervertebral disc annulus

> Vertebral body and disc space replacement devices

~ 00557