Disclosed in one embodiment is a medical device including an expandable
metal vascular stent including at least one surface. A coating layer
including parylene or a parylene derivative is positioned on the at least
one surface. At least one layer comprising a bioactive agent is
positioned on the coating layer, wherein the bioactive agent is selected
from the group consisting of an immunosuppressive agent,
anti-inflammatory agent and an anti-proliferative agent. A porous layer
is positioned on the at least one layer including a bioactive agent,
wherein upon implantation into a patient, the porous layer controls
release of the bioactive agent from the at least one layer including the
bioactive agent.