Compounds of formula (I) or a pharmaceutically acceptable salt, solvate or
prodrug thereof, are disclosed: ##STR00001## wherein R.sup.1 is
C.sub.1-6alkyl, haloC.sub.1-6alkyl, C.sub.2-6alkenyl, amino,
monoC.sub.1-4alkylamino or diC.sub.1-4alkylamino; R.sup.2 and R.sup.3,
which may be the same or different, are hydrogen, halogen,
C.sub.1-6alkyl, haloC.sub.1-6alkyl, C.sub.1-4alkoxy, haloC.sub.1-4alkoxy,
cyano, amino, monoC.sub.1-4alkylamino or diC.sub.1-4alkylamino; each
R.sup.4, which may be the same or different, is C.sub.1-6alkyl, halogen,
C.sub.1-6alkyl, haloC.sub.1-6alkyl, C.sub.1-4alkoxy, haloC.sub.1-4alkoxy,
cyano, nitro, amino, monoC.sub.1-4alkylamino or diC.sub.1-4alkylamino; p
is 0, 1 or 2; n is 1 or 2; R.sup.5 and R.sup.6, which may be the same or
different, are hydrogen, halogen, C.sub.1-6alkyl, haloC.sub.1-6alkyl,
C.sub.1-4alkoxy, haloC.sub.1-4alkoxy, cyano, amino,
monoC.sub.1-4alkylamino or diC.sub.1-4alkylamino; and Het is thienyl,
pyridyl, pyrimidinyl, pyridazinyl, pyrimidinyl, pyrazinyl, imidazolyl,
pyrazolyl, pyrrolyl, quinolyl, thiazolyl or furyl, each of which may be
substituted by one or more groups independently selected from the list
consisting of C.sub.1-6alkyl, C.sub.1-6alkoxy, acetyl, halogen,
haloC.sub.1-6alkyl, cyano, nitro, amino, monoC.sub.1-4alkylamino and
diC.sub.1-4alkylamino. Methods of preparation of the compounds, and uses
thereof in medicine, for example treatment of schizophrenia, are also
disclosed.