A system, method and computer program product for controlling disease at
an end user location, including (a) testing a range of candidates
including at least one of: (i) Bacillus species, (i) Bacillus strains,
(iii) species of beneficial bacteria (iv) strains of beneficial bacteria
and (v) strains of beneficial bacterial viruses, against samples
including at least one of pathogenic Vibrio, Gram negative pathogenic
bacteria and Gram positive pathogenic bacteria taken from an end user
location; (b) performing at least one of the following steps: (i)
selecting one or more of the candidates that one of inhibit and attack at
least one of the samples by direct inhibition of at least one of in situ
antibiotic production, competitive exclusion, production of enzymes that
degrade quorum sensing molecules, and (ii) testing a range of quorum
sensing inhibitor compounds against the samples; and (c) performing the
steps (a) and (b) for the end user location, including one of a country,
major region and individual end user location, to target microbial
technology to use in bio-control of disease specific to the end user
location.