A necrosis assays is performed with a cell expressing RIPK1 and RIP3 by (a) culturing the cell with a smac mimetic, caspase-8 inhibitor and TNF-.alpha.; and (b) detecting a resultant necrosis of the cell.

 
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< Pharmaceutical compositions based on fluorenecarboxylic acid esters and soluble TNF receptor fusion proteins

> Tumor necrosis factor combined with interferon in demyelinating diseases

> Pharmaceutical compositions for the treatment of TNF-.alpha. related disorders
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