A method and oligonucleotides for targeted nucleotide exchange of a duplex
DNA sequence, wherein the donor oligonucleotide contains at least one
modified nucleotide having a higher binding affinity compared to
naturally occurring A, C, T or G and/or binds stronger to a nucleotide in
an opposite position in the first DNA sequence as compared to a naturally
occurring nucleotide complementary to the nucleotide in the opposite
position in the first DNA sequence.