The present invention provides a method of crystallization of bicalutamide comprising adding an acetone solution containing bicalutamide to water; crystals of bicalutamide wherein particle size distribution of the crystals is 1 to 10 .mu.m of Dp.sub.10, 10 to 25 .mu.m of Dp.sub.50 and 25 to 100 .mu.m of Dp.sub.90, and the crystals are obtainable by the method described above; and crystals of bicalutamide, wherein particle size distribution of the crystals is 1 to 3 .mu.m of Dp.sub.10, 2 to 5 .mu.m of Dp.sub.50 and 5 to 15 .mu.m of Dp.sub.90.