An antenna for use in connection with a combined RFID reader and optical imager. A printer circuit board having a wire loop positioned thereon and a hole formed therethrough is positioned in combination with an optical imager so that the imaging element of the optical imager may capture images through the hole. In addition, illuminating elements, such as LEDs may be provided on the printed circuit board to provide external or additional illumination of target objects. By positioning the antenna and optical imager in such a manner, the space required to implement optical imaging and RFID capabilities is improved and optical imaging and RFID interrogation may be more easily directed at a single object. In addition, extra illumination may be easily provided for improved imaging.