A method and apparatus for performing a calibration and navigation of a member. The member may be calibrated relative to a selected portion, such as a sensor on an instrument. The calibrated member may then be navigated with a selected system. The calibration technique can be infinitely flexible and not rigid or designed for specific components. Moreover, the calibration may occur when the member is interconnected to an end of the instrument that is non-co-axial with another end of the instrument.