An approach to performing graph-based computation uses one or both of an efficient startup approach and efficient control using process pools. Efficient startup of a graph-based computation involves precomputing data representing a runtime structure of a computation graph such that an instance of the computation graph is formed using the precomputed data for the required type of graph to form the runtime data structure for the instance of the computation graph. Pools of processes that are each suitable for performing computations associated with one or more vertices of the computation graphs are formed such that at runtime, members of these pools of processes are dynamically assigned to particular vertices of instances of computation graphs when inputs are available for processing at those vertices.