Systems and methods for synchronizing data stores. A framework including a sync runtime enables consistent and manageable synchronization between a data store and multiple, diverse back end data stores. The sync runtime provides services such as change enumeration, conflict detection, metadata management, item ID matching, sync interruptability, and the like that are accessible to configurable adapters over an application programming interface. Each synchronizing data store can uses a sync controller to initialize an adapter that can access the services provided by the sync runtime. The sync controller can use a profile to configure each adapter. The profile can identify conflict resolution policies, synchronization filters, source and destination folders, sync direction, and the like.