A method and system for determining the three-dimensional location of a mobile wireless device. In one implementation, the device is a cellular telephone making a 911 call from one floor of a multi-story building. An embodiment of the method of the invention includes establishing a database that associates transmission metrics with altitudes of x-y coordinate locations having more than one altitude at which the mobile wireless device could be located, receiving a communication from the mobile wireless device, determining an x-y coordinate location of the mobile wireless device, measuring a transmission metric of the mobile wireless device, and consulting the database to determine the altitude from the x-y coordinate location and the measured transmission metric. The transmission metric could be, for example, the transmission time or angle of arrival of a wireless signal received from the mobile wireless device.