An anti-AIDS agent which comprises, as the active ingredients, one or more components selected from the group consisting of Melastoma villosum Lodd., Dipterocarpus obtusifolius Teijsm ex Miq., Lyophyllum aggregatum, Dictyophora indusiata, pu-erh tea, mentha and stevia. Since the foods having been confirmed as safe in practice are employed, this agent is completely safe to take over a long time.