An encryption and decryption apparatus includes a round key generator generating at least one round key for iterative operations in each of a plurality of rounds using an input key for one of the encryption and decryption; an initial round key adder receiving a plurality of divided parts of an input data, consecutively receiving a plurality of parts of an initial round key which is output from the round key generator for an initial round and corresponds to each of the divided input data, and adding the input data and the corresponding part of the initial round key; a first operator receiving a first data which is output from the initial round key adder and a part of the round key which is output from the round key generator and performing operations for one of the encryption and decryption; a second operator receiving a second data which is output from the initial round key adder and another part of the round key which is output from the round key generator, and performing operations for one of the encryption and decryption; and a register part temporarily storing the first data which is output from the first operator and the second data which is output from the second operator, inputting the first and second data to the first and second operators, respectively, for operations of a next round among the plurality of the rounds, and outputting an encrypted or decrypted data when the plurality of the rounds are completed.